Institute of Cell Biology National Academy of Sciences of Ukraine

Department of Molecular Genetics and Biotechnology

The main research topics:

• Mechanisms of degradation of peroxisomal and cytosolic proteins in yeasts.


• Regulation of flavinogenesis in nonconventional yeasts. Cloning of structural and regulatory genes involved in biosynthesis of riboflavin and its derivatives (flavin coenzymes, roseoflavin) and its.


• Role of glutathione (GSH) in stress response of methylotrophic yeast cells: cloning of structural and regulatory genes, construction of GSH-overproducing strains, bioaccumulation of heavy metals.


• Production of biofuel ethanol by fermentation of lignocellulosic hydrolysates by non-conventional yeasts.


• Construction of microbial strains capable to produce isobutanol (yeasts) and hydrogen (bacteria).


• Biotechnological production of proteins important for medicine and diagnostics.


• Development of new combinatorial approaches for cancer treatment.