Institute of Cell Biology National Academy of Sciences of Ukraine

Department of Analytical Biotechnology

Research Grants

Current International Grants:

1. 2008-2009 STCU-4378 "Gene and Protein Engineering of Oxidoreductases for Construction of Bionanosized Objects of Analytical Importance".


2. 2008 NATO Linkag Grant PDD (CP)-(CPP.NUKR.CLG 982955) "Novel Electrochemical and Optical Nanostructured Sensors for Detection of Disease-Related Ions".


3. NATO Linkage Grant LST.NUKR.CLG 980621 "Novel Biological and Chemical Sensors for Formaldehyde Monitoring in Wasteswaters, Foodstuffs and Pharmaceuticals".


4. 2008-2010 NATO Linkage Grant PDD (CP)-(CPP.NUKR.CLG 982955) "Bio/Chemical Sensors for Detection of Toxins in Fish Meat”, STCU-project 4378 „Gene and Protein Engineering of Oxidoreductases for Construction of Bionanosized Objects of Analytical Importance".


5. 2008-2010 Ukrainian-Russian F28/454 "Structural and functional characterization of alcohol oxidase from thermotolerant methylotrophic yeast Hansenula polymorpha".


6. 2010 Ukrainian-izrailan M157 "Control of formaldehyde content in air by biosensor based on formaldehyde dehydrogenase and its removing by bioreactor with immobilized alcohol oxidase".


7. 2010-2011 CRDF UKB2-9044-LV-10 "Production of trial series and preparation of technical documentation for bioanalytical kit for enzymatic analysis of l-lactate in clinical diagnostics and beverage industries".


8. 2010-2011 CRDF UKB1-9048-KV-10 "Development of technology for production of recombinant human arginase as anticancer enzyme and element of biosensor for arginine".


9. 2010-2011 Polish-Ukrainian N 304 326136 "Mutants of nonconventional yeasts for efficient chromate bioremediation, recovery and industrial waste-water purification".


10. 2012-2015 NATO scientific project in the frame of the Program "Science for Peace and Security" SPS(NUKR)SFPP 984173 "Novel electrochemical Nano-Sensors for toxic ions Detection" (2012-2013).


11. 2013-2015 Polish-Ukrainian "Scientific integration of the Polish-Ukrainian borderland area in the field of monitoring and detoxification of harmful substances in environment".

National scientific projects:

1. 2010-2012 CRDF.



Project 1. UKB2-9044-LV-10 "Production of trial series and preparation of technical documentation for bioanalytical kit for enzymatic analysis of l-lactate in clinical diagnostics and beverage industries".




Project 2. CRDF UKB1-9048-KV-10 "Development of technology for production of recombinant human arginase as anticancer enzyme and element of biosensor for arginine".



2. 2009-2012 Ukrainian-Russian F28/454 "Structural and functional characterization of alcohol oxidase from thermotolerant methylotrophic yeast Hansenula polymorpha".


3. 2003-2006 Program "Physiological, biochemical and molecular genetic bases of living systemsʼ functioning and development of principles for their management".



Theme: "Biotechnological production and functional characteristics of the proteins, important for diagnostics and treatment".




Task: "Development of the effective systems for purification of oxido-reductases from microbial cells".



4. 2003-2006 Program "Investigations in the field of sensorsʼ systems and technologies".



Project 1. "Construction of the enzymesʼ elements of sensors on the base of oxido-reductases to control the content of lactate and ethanol in biological fluids and fermentation broths".




Project 2. "Development of the new biosensorsʼ and enzymatic systems for analysis of glycerol in alcoholic beverages and triglycerides in biological fluids".




Project 3. "Construction of amine oxidase over-producing yeast strains and development of biosensor for assay of natural amines in food and in human biological fluids".



5. 2007-2012 Program "Sensorsʼ systems for medical-ecological and industrial-technological requirements".



Project 1. "Development and production of the experimental samples of electrochemical biosensors for assay of formaldehyde in foods".




Project 2. "Portative analyzer based on amperometric enzyme biosensors for the quality control of the beverages in wine-making".



6. 2010-2012 Program "Biomass as a fuel source (biofuel)".



Project 1. "Screening and selection of the thermotolerant Saccharomycetes strains with enhanced ethanol-producing activity".



7. 2013-2014 Program "Sensorsʼ devices for medical-ecological and industrial-technological requirements: meteorological support and research exploitation".



Project 1. "The development of bio / chemosensor analyzers for determination of formaldehyde, L- and D-lactate, their metrological evaluation and experemental testing. The construction of amperometric analyzer for assay of formaldehyde,L- and D-lactate based on the device "FORMATEST-2010".




Project 2. "The development and trial exploitation of a portative analyzer based on amperometric enzyme biosensors for quality control of beverages in winery. Development of biosensor methods of arginine analysis in wine by using arginine-hydrolyzing recombinant enzymes".



8. 2013-2014 Program "Biological resources novel technologies of bioenergy conversion".



Project 1. "Screening and selection of the thermotolerant Saccharomycetes strains – overproducers of bioethanol using mutagenesis".