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Institute of Cell Biology National Academy of Sciences of Ukraine

 

Department of Regulation of Cell Proliferation and Apoptosis

 

Research Grants

 

International Grants


  1. "The role of transforming growth factors in the mechanisms of hyperthermia action on the proliferation of tumor and normal mammalian cells" (CDA-NIS Program, National Cancer Institute (NIH, USA), 1995-1998) – Principal Investigator – Stoika R.S.
  2. "Expression of Smad tumor suppressor genes in breast and colorectal cancers" (The Royal Swedish Academy of Sciences (Sweden), 1997-1998) – Co-Principal Investigator – Stoika R.S.
  3. "Transforming growth factor beta signalling in human breast cancer: study of ligand, receptors, Smad proteins expression and intactness of the signalling" (The Royal Swedish Academy of Sciences (Sweden), 2000-2001) – Co-Principal Investigator – Stoika R.S.
  4. "Changes in plasma membrane glycoproteins at cell death and their role in development of autoimmune diseases" (Grant from Ministry of education and science of Federative Republic of Germany for collaboration with the Ministry of education and science of Ukraine 2009-2011) – Co-Principal Investigator – Stoika R.S.
  5. "Functionally active colloid carriers for chemical, biological and microelectronic technologies" (Grant #1930 from Science and Technology Center of Ukraine, 2004-2006) – Principal Investigator – Dr.Chem.Sci. Zaichenko O.S., team leader – Stoika R.S., corresponding member of NAS of Ukraine.
  6. "Information videoscope of ultrahigh resolution for investigation of programmed death (apoptosis) of human tumor cells" (Grant #1702 from Science and Technology Center of Ukraine, 2004-2006) – Co-Principal Investigator – Stoika R.S.
  7. "Novel functiоnal luminescent polymer and hybrid nanoparticles and nano-assembles with directed chemical and physical characteristics" (Grant #4140 from Science and Technology Center of Ukraine, 2007-2008) – Principal Investigator – Dr.Chem.Sci. Zaichenko O.S., team leader – Stoika R.S., corresponding member of NAS of Ukraine.
  8. "Nаnоscale systems fоr delivery of anticancer substances based on novel luminescent and X-ray detectable oligoelectrolytes" (Grant #4953 from Science and Technology Center of Ukraine, 2009-2011) – Principal Investigator – Stoika R.S., corresponding member of NAS of Ukraine, team leader – assoc. prof. Zaichenko O.S.
  9. "Novel functional nanomaterials for enhancement of the efficiency of chemotherapy" (Grant #6256 from Science and Technology Center of Ukraine, 2017-2019) – Co-Principal Investigator – Stoika R.S.
  10. "Lаndomycin А – a new preparation for chemotherapy of drug-resistant tumors: production, preclinical study, marketing" (CRDF grаnt №FSCX-14-60609-0 (USА – Ministry of education and science of Ukraine), 2015-2017) – Principal Investigator – Stoika R.S.
  11. Grant for 100 best scientific teams that collaborate with Shandong Academy of Sciences (Іnstitute of Biology, Jinan, Shandong province, Peoples Republic of China, 2020-2022) – Principal Investigator – Stoika R.S., corr. member of NAS of Ukraine.
  12. Bilateral Ukraine-Austria cooperation project "New approaches to the treatment of metastatic tumors resistant to chemotherapy, based on the angucycline antibiotic landomycin A immobilized on a poly(2)-oxazoline carrier" – State registration number 0119U102525, 2019-2020 – Scientific supervisor – Panchuk R.R., Dr.Sc. Co-executor in Austria – Institute for Cancer Research, Medical University of Vienna.
  13. Bilateral Ukraine-Austria cooperation project “Dual action on specific vulnerabilities of malignant cells by new thiosemicarbazone derivatives” – Contract dated 12.09.2023 No.M/88-2023, Contract dated 22.05.2024 No.M/30-2024, 12.09.2023-31.12.2024 – Scientific supervisor – Stoika R.S. Corresponding Member of the NAS of Ukraine, Doctor of Biological Sciences, Professor, Head of Department. – Co-executor in Austria – Institute of Cancer Research, Medical University of Vienna.

 

Grants from Ukrainian Organizations


  1. "Study of signaling mechanisms of apoptosis induction depending on the types of inducer and target cells in vitro and in vivo" – NASU project (2006-2010) – scientific supervisor (PI) – corresponding member of NASU R.S. Stoyka
  2. "Mechanisms of action in vitro and in vivo of new compounds with proapoptotic activity, ways to increase the effectiveness of their antineoplastic action and justification of new approaches in diagnostics and assessment of the development of autoimmune and hemato-oncological diseases" – NASU project No.: iii-3-12 (2011-2016) – scientific supervisor – corresponding member of NASU R.S. Stoyka
  3. "Increasing the efficiency of traditional and experimental drugs in vitro and in vivo by immobilizing them on nano-sized carriers and combining them with antioxidants" – NASU Project No.: III-3-17 (2017-2021) – scientific supervisor – corresponding member of NASU Stoika R.S.
  4. "Increasing the efficiency of target gene delivery to plants using new nano-sized polycationic polymers" – jointly with the state institution "Institute of Food Biotechnology and Genomics" NASU) project No.32f, 2015-2019 – scientific supervisor – corresponding member of NASU Stoika R.S.
  5. "New approaches to overcome tumor resistance to chemotherapy caused by deregulation of the cellular glutathione system" – Ukrainian-Belarusian project of the DFFD of Ukraine (2019-2020) – supervisor – corresponding member of the NAS of Ukraine Stoika R.S.
  6. "Antitumor effect of chemotherapeutic drugs under the conditions of their delivery by new nanocomposite carriers functionalized with N-acylethanolamines" – Project No.5.9.1.50 of the state target scientific and technical program "nanotechnologies and nanomaterials" (2010-2014) – PI and responsible executor – Ph.D. Panchuk R.R.
  7. "New biocompatible polymer nanocomposites with encapsulated fluorescein: their biofunctionalization and effect on cells" – Project No.101/10N of the Targeted Comprehensive Program of Fundamental Research of the National Academy of Sciences of Ukraine "Nanostructural Systems, Nanomaterials, Nanotechnologies" (2010-2014) – PI and Responsible Executor – Ph.D. Panchuk R.R.
  8. "Study of Molecular Mechanisms of Action and Antitumor Activity of Novel Biologically Active Substances" – Presidential Grant for Support of Research of Young Scientists No.gp/f32/192-2011 (2011) – Responsible Executor – Ph.D. Panchuk R.R.
  9. "New Nanoscale Drug Delivery Systems to Target Cells" – Presidential Grant for Support of Research of Young Scientists No.Gp/F36/408-2012 (2012) – PI and Responsible Executor – Ph.D. Panchuk R.R.
  10. "Mechanisms of cytotoxic activity of angucycline antibiotic landomycin E on tumor cells" – Ukrainian-Austrian bilateral projects – No.m/577-2011 and m/246-2012 (2011-2012) – PI and responsible executor – Ph.D. Panchuk R.R.
  11. "Inhibition of growth of experimental tumors with high aerobic glycolysis: development of new approaches based on metabolomics" – Presidential Grant for Gifted Youth (2013) – PI and responsible executor – Ph.D. Panchuk R.R.
  12. "Use of redox-modulating compounds to increase the selectivity of action of new antitumor drugs" – Ukrainian-Belarusian bilateral project No.F54/185-2013 (2013) – responsible executor – Ph.D. Panchuk R.R.
  13. "Enhancement of the antineoplastic activity of novel antitumor drugs using combined chemotherapy approaches and improved drug delivery to malignant cells" – Ukrainian-Austrian bilateral project No.M/3-2013 and No.M/112-2014 (2013-2014) – responsible executor – Ph.D. Panchuk R.R.
  14. "Combining metabolomics approaches and new chemotherapeutic agents in the treatment of lymphomas and leukemias" – Presidential Grant to Support Research of Young Scientists No.F61/96-2015 (2015) - responsible executor – Ph.D. Panchuk R.R.
  15. "Redox modulation of the glutathione system in tumor cells with different sensitivity to chemotherapy". Ukrainian-Belarusian bilateral project No.f73/85-2016 and f73/55-2017 (2016-2017) – responsible executor – Ph.D. Panchuk R.R.
  16. "Molecular mechanisms of the modulatory action of antioxidants on the therapeutic activity of new anticancer drugs" – Presidential Grant to Support Research of Young Scientists No.F70/79-2017 (2017) – responsible executor – Ph.D. Panchuk R.R.
  17. "New approaches to the treatment of metastatic tumors resistant to chemotherapy based on the angucycline antibiotic landomycin A immobilized on a poly(2)-oxazoline carrier" – (2019-2020) Ukrainian-Austrian project – supervisor – Dr.Sc. Panchuk R.R.
  18. "Enhancement of the antitumor effect of landomycin A by immobilization on a poly-2-oxazoline nanoplatform: in vitro and in vivo effects" – Grant of the NAS of Ukraine to support research laboratories of young scientists (2018-2019) – supervisor – Dr.Sc. Panchuk R.R.
  19. "New biochemical approaches for assessing the ecotoxicity of metal-containing nanomaterials based on determining the characteristics of metallothioneins of aquatic animal species" - National Academy of Sciences of Ukraine (2010-2014) – Project leader – Corresponding Member of NAS U Stoika R.S., Co-leader – Doctor of Biological Sciences Stolyar O.B., Group leader – Doctor of Chemical Sciences Zaichenko O.S.
  20. "Use of effective oligoelectrolyte systems for gene delivery for the purpose of genetic transformation of plant cells" – National Academy of Sciences of Ukraine (2010-2014). Project leader – Corresponding Member of NAS U Stoika R.S., Group leader – Doctor of Chemical Sciences Zaichenko O.S.
  21. "Creation of unified systems based on functional nanocarriers for the detection and isolation of pathogenic factors of biological origin" – National Academy of Sciences of Ukraine (2010-2014) – Co-leader of the project – Corresponding Member of the NAS of Ukraine Stoika R.S.
  22. "New biocompatible nanocomposites with encapsulated fluorescein: their biofunctionalization and effect on cells" – National Academy of Sciences of Ukraine (2010-2014) – Project leader – Corresponding Member of the NAS of Ukraine Stoika R.S., Group leader – Doctor of Chemical Sciences Zaichenko O.S.
  23. "Antitumor effect of chemotherapeutic drugs when delivered by new nanocomposite carriers functionalized with N-acylethaneamines" – National Academy of Sciences of Ukraine (2010-2014) – Co-leader of the project – Corresponding Member of the NAS of Ukraine Stoika R.S., group leader – Doctor of Chemical Sciences Zaichenko O.S., executor – Doctor of Biological Sciences Panchuk R.R.
  24. "Mechanisms of action in vitro and in vivo of new compounds with proapoptotic activity, ways to increase the effectiveness of their antineoplastic action and justification of new approaches in the diagnosis and assessment of the development of autoimmune and hemato-oncological diseases" – NAS of Ukraine, state registration number 0112U002174 (2012-2016) – supervisor – Corresponding Member of the NAS of Ukraine Stoika R.S.
  25. "Improving the efficiency of target gene delivery to plants using new nanosized polycationic polymers" - NAS of Ukraine, grant of the targeted complex interdisciplinary scientific research program of NAS of Ukraine "Molecular and cellular biotechnologies for the needs of medicine, industry and agriculture" – 2017-2019 supervisor – Corresponding Member of the NAS of Ukraine Stoika R.S.
  26. "Target gene delivery into mammalian cells using novel native biocompatible polymeric nanomaterials" – Program-targeted and competitive topics of the NAS of Ukraine - Grants of the NAS of Ukraine to research laboratories/groups of young scientists of the NAS of Ukraine for conducting research in priority areas of science and technology development 2020-2021, state registration number 0120U100197 (2020-2021) – supervisor - Finiuk N.S., Ph.D.
  27. "Interrelations between immunomodulatory and antitumor actions of new heterocyclic compounds (thiazole and 4-thiazolidinone derivatives)". Program-targeted and competitive topics of the NAS of Ukraine, state registration number 0120U103077 (2020-2022) – supervisor – Dr.Sc. Lootsyk M.D.
  28. "Novel Dual Inhibitors of Casein Kinase 2 and Histone Deacetylase for Targeted Tumor Chemotherapy" - NAS of Ukraine, grant to research groups of young scientists of NAS of Ukraine for conducting research in priority areas of development of science and technology 2021-2022, state registration number 0121U110732 (2021-2022) – Scientific supervisor – Dr.Sc. Panchuk R.R.
  29. Departmental topic "The role of immunomodulatory in the antitumor action of traditional and experimental medicines at their delivery by polymeric nanocarriers to various target cells in vitro and in vivo" – state budget topic of the NAS of Ukraine, state registration number 0122U002240 (2022-2026) – supervisor – Corresponding Member of the NAS of Ukraine Stoika R.S.
  30. "Enhancement of biological activity of berberine-like derivatives via their covalent and non-covalent modifications" - NAS of Ukraine, under the budget program "Support for the development of priority areas of scientific research" – OK 0222U005151 (2022) – supervisor – Corresponding Member of the NAS of Ukraine Stoika R.S.
  31. "Anti-inflammatory and wound-healing agent containing the composition of the cannabimimetic N-stearoylethanolamine with chitosan hydrogel" – Grant of the National Research Foundation of Ukraine, competition "Science for the reconstruction of Ukraine in the war and post-war periods", registration number 2022.01/0207, state registration number 0123U103497 (2023-2024) – supervisor – Corresponding Member of the NAS of Ukraine Stoika R.S.
  32. "Molecular design, synthesis and preclinical testing of new thiazole and thiazolidine derivatives with selective action on cells of myeloproliferative neoplasms" – Grant of the National Research Foundation of Ukraine, competition "Advanced Science in Ukraine", registration number 2023.03/0104, state registration number 0124U003835 (2024-2026) – supervisor (PI) – Finiuk N.S., Ph.D.
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