Institute of Cell Biology National Academy of Sciences of Ukraine

Department of Regulation of Cell Proliferation and Apoptosis

The main areas of scientific research in the department:

1. Structural-functional relationships in the antineoplastic (in vitro) and antitumor (in vivo) action of new synthetic and natural compounds of different chemical structures.


2. The role of apoptosis in the mechanisms of action of new heterocyclic compounds (thiazoles, thiazolidinones, and their hybrids with other substances).


3. Mechanisms of action of new thiosemicarbazones as reactivators of mutant forms of the p53 protein. The role of immunogenic cell death in carcinogenesis.


4. Mechanisms of enhancing the action of biologically active substances when they are delivered to target cells by nanosized materials of synthetic and natural origin. The use of novel polymeric nanomaterials for the delivery of nucleic acids to target cells of different origins (microorganisms, mammalian, and plant cells).


5. Creation of composite materials for the treatment of superficial wounds, including infected ones.