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Institute of Cell Biology National Academy of Sciences of Ukraine

 

Conditions for study and residence of foreigners and stateless persons

 

The Institute of Cell Biology of the NAS of Ukraine conducts educational activities using information resources, training equipment, laboratories, other objects, which confirm the ability of the educational institution to carry out educational activities in the stated amounts under the previously obtained license with the corresponding licensed amounts.

 

Use of information resources.

 

The official website of the Institute of Cell Biology of the NAS of Ukraine http://www.cellbiol.lviv.ua a (hereinafter referred to as the Institute) contains basic information about the activity of the educational establishment.

 

To ensure the qualitative training of specialists in the specialty 091 – Biology at the Institute at the appropriate level, the work has been organized on the organization of information support of the educational process. Thus, for carrying out self-study library operates a total area of 24.3 m2 for 15 seats.

 

The library provides an access to periodical editions in English in a relevant or related profile, educational and scientific information on a variety of media (textbooks, manuals, domestic and foreign professional periodicals) in sufficient numbers.

 

The volume of funds of the educational and scientific literature consists of 1,203 copies (in addition to the Licensing Terms of the “Information on the provision of educational program”). The mode of operation of the library is set taking into account the needs of the educational process and the intensity of visits by its participants.

 

The premises of the scientific library provide an access for teachers and postgraduate students to the Internet (the Institute has a gigabit access channel), which creates the conditions for expanding the possibilities of obtaining the necessary information during educational and scientific activities. There is also access to a paid digital resource, Web of Science, which houses scientific literature and patents, according to the agreement of the ICB NASU with the e-VERUM Consortium.

 

The Institute's library provides at least five national and foreign professional periodicals of the corresponding or related specialty profile 091 – Biology, whose names are presented in the Higher Education Information Support Sheets.

 

On the whole, the library provides an access to educational and scientific information, enhancement of knowledge, effective development of educational and scientific activities and meeting the information needs of teaching staff and graduate students.

 

Use of educational equipment of laboratories.

 

To carry out the preparation of Doctors of Philosophy at the Institute of Cell Biology of the NAS of Ukraine, an appropriate material and technical base was created, which allows to carry out the training of postgraduate students of the specialty 091 – Biology, taking into account the amount of the licensed amount.

 

The area of ​​educational premises at Drahomanov Street, Building. 14/16, Lviv, 79005, is 130.4 m2, including: rooms for student's classes (lecture rooms, classrooms, classrooms, laboratories, etc.) – 106.1 m2, computer labs – 24.3 m2.

 

The Institute has an conference hall of 72.1 m2 for lectures on subjects of cycles of vocational, as well as general training; organizational, festive events, and others.

 

The computer lab is located at the library, equipped with a PC (3 units with a maximum life of 8 years). Available equipment allows one to conduct courses in disciplines according to the curriculum using a modern software base with the use of educational multimedia programs.

 

The equipment of laboratories and the assembly hall necessary for providing the educational process for the training of specialists in the specialty 091 – Biology of the third educational-scientific level of education for the Doctorate of Philosophy, is presented in the Data on the quantitative and qualitative indicators of logistical support of educational activity in the field of higher education. The equipment and equipment of 2 laboratories is intended to ensure the implementation of the practical component of the educational and scientific program of IBK NAS of Ukraine. 12 postgraduate students can do practical work at the same time. In stock modern laboratory furniture. Modern equipment allows to carry out an experimental part of practical classes in accordance with the working and educational programs of the disciplines of the cycle of vocational training: Cytology and histology; Regulation of cell proliferation, differentiation and apoptosis; General Microbiology; Physiology and Biochemistry of Microorganisms; Microbial Production of Proteins; Methods of Cell Biology; Animal Cell Biochemistry.

 

In all the classrooms, the proper conditions have been created to ensure the wide access of the postgraduate students and the teaching staff of the Institute to the Internet.

 

Provision of facilities used in the educational process for postgraduate studies (lecture rooms, lecture rooms, classrooms, laboratories, etc.), except for the area at Drahomanov Street, Building. 14/16, Lviv, 79005, is carried out in accordance with the Order of the Presidium of the NAS of Ukraine, N 328, dated by 30.05.2016, and the Agreement on Cooperation in the field of scientific studies and carrying out of educational activity of the third (educational-scientific) level of higher education for the purpose of preparation of Doctors of Philosophy between the Institute of Cell Biology of NAS of Ukraine and Lviv National University named after Ivan Franko of Ukraine dated by 13.03.2019.

 

Accommodation.

 

Provision with a hostel and medical center, is in accordance with the Order of the Presidium of NAS of Ukraine, N 310, dated by May 24, 2016 “On providing postgraduate students of scientific institutions of the NAS of Ukraine with dormitories and providing them with medical services and the Agreement on Cooperation in the field of scientific research and conducting educational activities of the third (educational (scientific) level of higher education for the preparation of PhDs between the Institute of Cell Biology of the NAS of Ukraine and the Ivan Franko National University of Lviv in Ukraine, dated by 13.05.2019.

 

Thus, the preparation of postgraduate students in the specialty 091 – Biology of the third educational-scientific level of education in the field of knowledge 09 – Biology is fully equipped with training classrooms, specialized laboratories and offices, equipment and equipment necessary for the implementation of the educational training program for specialists.

Institute of Cell Biology National Academy of Sciences of Ukraine

 

Ukrainian | English

Institute of Cell Biology National Academy of Sciences of Ukraine

 

Department of Molecular Genetics and Biotechnology

 

Head of the Department - Andriy Sibirny, Ph.D., Dr. Sci., Professor, Member of NAS of Ukraine.

 

The Department was established in 1988 on the base of the Laboratory of Biochemical Genetics which was found in 1985, and since that time it is headed by Andriy Sibirny, Dr.Biol.Sci., Professor, Member of National Academy of Sciences of Ukraine. He was awarded with O. Palladin prize of NAS of Ukraine in the field of biochemistry (2004) and I. Metchnikov prize of NAS of Ukraine in the field of microbiology (2014). He is the laureate of State award for the achievements in science and technology (2012). A. Sibirny is also honored worker of Ukraine in science and technology (2008). A. Sibirny is the author of more than 220 full-length scientific articles including three monographs and near 150 papers in peer-reviewed International scientific journals, 28 Patent Applications, 100 abstracts of oral and poster communications of conferences, including 40 plenary lectures on domestic and International scientific meetings.

Ukrainian | English

Institute of Cell Biology National Academy of Sciences of Ukraine

 

Department of Molecular Genetics and Biotechnology

 

The main research topics:

 

  • Mechanisms of degradation of peroxisomal and cytosolic proteins in yeasts.

  • Regulation of flavinogenesis in nonconventional yeasts. Cloning of structural and regulatory genes involved in biosynthesis of riboflavin and its derivatives (flavin coenzymes, roseoflavin) and its.

  • Role of glutathione (GSH) in stress response of methylotrophic yeast cells: cloning of structural and regulatory genes, construction of GSH-overproducing strains, bioaccumulation of heavy metals.

  • Production of biofuel ethanol by fermentation of lignocellulosic hydrolysates by non-conventional yeasts.

  • Construction of microbial strains capable to produce isobutanol (yeasts) and hydrogen (bacteria).

  • Biotechnological production of proteins important for medicine and diagnostics.

  • Development of new combinatorial approaches for cancer treatment.
Ukrainian | English

Institute of Cell Biology National Academy of Sciences of Ukraine

 

Department of Molecular Genetics and Biotechnology

 

Publications

 

Year Published scientific articles Total impact factor  
All Including articles in the
international journals
2008 15     View publications
2009 8     View publications
2010 6     View publications
2011 14     View publications
2012 4     View publications
2013 10     View publications
2014 12     View publications
2015 25     View publications
2016 17 11 43.747 View publications
2017 5 4 16.313 View publications
2018 8 5 19.530 View publications
2019 9 6 13.829 View publications
2020 20 11 50.745 View publications

2008

 

  1. Dmytruk O. V., Dmytruk K. V., Abbas C. A., Voronovsky A. Y., Sibirny A. A. Engineering of xylose reductase and overexpression of xylitol dehydrogenase and xylulokinase improves xylose alcoholic fermentation in the thermotolerant yeast Hansenula polymorpha // Microb. Cell. Fact. - 2008. – №. 7. - P. 21.
  2. Dmytruk O. V., Voronovsky A. Y., Abbas C. A., Dmytruk K. V., Ishchuk O. P., Sibirny A. A. Overexpression of bacterial xylose isomerase and own xylulokinase improves xylose alcoholic fermentation in the thermotolerant yeast Hansenula polymorpha // FEMS Yeast Res. – 2008. – Vol. 8, P. 165-173.
  3. Ishchuk O. P., Dmytruk K. V., Rohulya O. V., Voronovsky A. Y., Abbas C. A., Sibirny A. A. Development Of A Promoter Assay System For The Flavinogenic Yeast Candida famata Based On The Kluyveromyces Lactis ß-Galactosidase Lac4 Reporter Gene. // Enzyme Microbial Technology. – 2008. – Vol. 42,N3. – P. 208-215.
  4. Ishchuk O. P., Voronovsky A. Y., Stasyk O. V., Gayda G. Z., Gonchar M. V., Abbas C. A., Sibirny AA. Overexpression of pyruvate decarboxylase in the yeast Hansenula polymorpha results in increased ethanol yield in high-temperature fermentation of xylose. // FEMS Yeast Res. – 2008. – Vol. 8. – P. 1167-1174.
  5. Ksheminska H., Fedorovych D., Honchar T., Ivash M., Gonchar M. Yeast tolerance to chromium depends on extra-cellular chromate reduction and Cr(III)-chelation // Food Technol. Biotechnol. - 2008. - Vol.46, №4. – P.420-427.
  6. Lahtchev K. L., Batovska D. I., Parushev S. P., Ubiyvovk V. M., Sibirny A. A. Antifungal activity of chalcones: A mechanistic study using various yeast strains // Eur. J. Med. Chem. – 2008. - V.43, №10. - P. 2220-2228.
  7. Nazarko V. Y., Thevelein J. M., Sibirny A. A. G-protein-coupled receptor Gpr1 and G-protein Gpa2 of cAMP-dependent signaling pathway are involved in glucose-induced pexophagy in the yeast Saccharomyces cerevisiae // Cell Biol. Int. – 2008. - № 32. – P. 502- 504.
  8. Nazarko V. Y., Futej K. O., Thevelein J. M., Sibirny A. A. Differences in glucose sensing and signaling for pexophagy between the baker’s yeast Saccharomyces cerevisiae and the methylotrophic yeast Pichia pastoris // Autophagy. – 2008. - № 4. – P. 381- 384.
  9. Dmitruk KV, Smutok OV, Gonchar MV, Sibirnyĭ AA. Construction of flavocytochrome b2-overproducing strains of the thermotolerant methylotrophic yeast Hansenula polymorpha (Pichia angusta) // Mikrobiologia (Moscow). – 2008. - V.77. – P.213-218. (in Russian).
  10. Dmytruk O.V., Dmytruk K.V., Voronovsky A.Y., Sibirny A.A. Metabolic engineering of the initial stages of xylose catabolism in yeasts for construction of efficient producers of ethanol from lignocelluloses // Tsitologiia i genetika (Cytology and Genetics) – 2008. – Vol..42. – P.127-138.
  11. Sibirny V.А., Gonchar М.V., Grabek-Lejko D., Pavlishko H.М., Csöregi E., Sibirny A.A. Photometric assay of methanol and formaldehyde in industrial waste-waters using alcohol oxidase and 3-methyl-2-benzothiazolinone hydrazone // Intern. J. Environ. Anal. Chem. – 2008. – V. 88, N 4. – P. 289-301.
  12. Sibirny A. A., Voronovsky A. Y. Chapter 5: Candida famata (Debaryomyces hansenii). In: Yeast biotechnology: diversity and applications (G. Kunze, T. Satyanarayana Eds), Springer Science. 2008; Р. 83-110.
  13. Sibirny А.А, Boretsky Y.R. Chapter 6: Pichia guilliermondii. In: Yeast biotechnology: diversity and applications (G. Kunze, T. Satyanarayana Eds), Springer Science. 2008; РР 111-132.
  14. Klionsky D.J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (Review)// Autophagy. – V.4, №2. – P.151-175.
  15. Stasyk O.G., Maidan M. M., Stasyk O. V., Van Dijck P., Thevelein J.M., Sibirny A.A. Identification of hexose transporter-like sensor HXS1 and functional hexose transporter HXT1 in the methylotrophic yeast Hansenula polymorpha. Eukaryotic cell. – 2008. – Vol.7(4). – P.735-746.

2009

 

  1. Yatsyshyn, V.Y., Fedorovych, D.V., Sibirny, A.A. The microbial synthesis of flavin nucleotides: a review // Appl. Biochem. Microbiol. – 2009. – Vol. 45, No 2. – Р. 115–124.
  2. Pynyaha YV, Boretsky YR, Fedorovych DV, Fayura LR, Levkiv AI, Ubiyvovk VM, Protchenko OV, Philpott CC, Sibirny AA. Deficiency in frataxin homologue YFH1 in the yeast Pichia guilliermondii leads to missregulation of iron acquisition and riboflavin biosynthesis and affects sulfate assimilation // Biometals. – 2009. – Vol.22. - P.1051-1061.
  3. Cheon SA, Choo J, Ubiyvovk VM, Park JN, Kim MW, Oh DB, Kwon O, Sibirny AA, Kim JY, Kang HA. New selectable host-marker systems for multiple genetic manipulations based on TRP1, MET2 and ADE2 in the methylotrophic yeast Hansenula polymorpha // Yeast. – 2009. – Vol. 26, N9. - P.507- 521.
  4. Voronovsky AY, Rohulya OV, Abbas CA, Sibirny AA. Development of strains of the thermotolerant yeast Hansenula polymorpha capable of alcoholic fermentation of starch and xylan. // Metabolic Engineering. – 2009. – Vol. 11, N4-5. – P. 234-242.
  5. Ishchuk OP, Voronovsky AY, Abbas CA, Sibirny AA. Construction of Hansenula polymorpha strains with improved thermotolerance // Biotechnol. Bioeng. – 2009. – Vol.104, N5. – P. 911-919.
  6. Yatsyshyn VY, Ishchuk OP, Voronovsky AY, Fedorovych DV, Sibirny AA. Production of flavin mononucleotide by metabolically engineered yeast Candida famata. // Metabolic Engineering. – 2009. Vol.11, N3. – P. 163-167.
  7. Shkil H, Stoica L, Dmytruk K, Smutok O, Gonchar M, Sibirny A, Schuhmann W. Bioelectrochemical detection of L-lactate respiration using genetically modified Hansenula polymorpha yeast cells overexpressing flavocytochrome b(2) // Bioelectrochemistry. 2009, 76(1-2):175-9
  8. Fedorovych D., Gonchar M., Ksheminska H., Prokopiv T., Nechay H., Kaszycki P., Koloczek H., Sibirny A. Mechanisms of chromate detoxification in yeasts // Miсrobiology and Biotechnology. - 2009. – №.7. – С.15-21

institut(at)cellbiol.lviv.ua